Abstract Background Glioblastoma (GBM) is the most common brain tumor with the worst prognosis.Temozolomide is the only first-line drug for GBM.Unfortunately, the resistance issue is a classic problem.Therefore, it is essential to develop new drugs to treat GBM.As an oncogene, Skp2 is involved in the pathogenesis of various cancers including GBM.In
A large scale profiling and analysis of glycerophospholipid species in macrophages has facilitated the identification of several rare and atypical glycerophospholipid species.By using liquid chromatography tandem mass spectrometry and Colloidal Silver comparison of the elution and fragmentation properties of the rare lipids to synthetic standards,
Abstract Background Animal models of human diseases are often used in biomedical research in place of human subjects.However, results obtained by animal models may fail to hold true for humans.One way of addressing this problem is to make animal models more similar to humans by placing human tissue into animal models, rendering them chimeric.Since
Embryonic toxicity of lambda-cyhalothrin (LCH) and the mitigating properties of extra virgin olive oil (EVO) and vitamin E were investigated in golden black variety of chick embryos.Fifty fertilized Stash Cans eggs distributed in 5 groups received their respective group treatments at zero days of incubation were recovered after 14 days of incubatio